Transfection is the process of introducing nucleic acid into a cell. NPL can measure the formation and uptake of drug delivery vectors and their cargo into cells. We employ biophysics, microscopy and cell biology to characterise and measure uptake and biological activity of nucleic acid and protein cargo delivered to cells. To aid comparative measurements of uptake we can prepare vector standards with well characterised properties and bio-activity, to support higher order reference measurements.
We use microscopy techniques to try to address:
Various bioassay, biophysical and imaging techniques provide a comprehensive characterisation of nucleic acid and vaccine drug delivery. These services are delivered using the following equipment:
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Our team of experts develops and uses range of cutting-edge measurement tools and methods to create new treatments and diagnostics, as well as make current ones more effective.
We develop cutting edge measurement tools and methods to unlock new applications, from drug discovery to synthetic biology. Our knowledge of biophysical measurements helps us understand the relationship between biological systems and processes.
Our research and measurement solutions support innovation and product development. We work with companies to deliver business advantage and commercial success.
Contact our Customer Services team on +44 20 8943 7070