We use a range of optical microscopy techniques, many are fluorescence-based, to visualise and quantify the properties of biological systems. We can examine:
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Method |
Summary |
Good for |
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Structured Illumination Microscopy (SIM)
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Fast (up to ~ 20 frames per second) super-resolution imaging (lateral resolution ~ 130 nm) |
2D cell cultures, some 3D systems. Live cell imaging. Subcellular dynamics |
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Confocal Laser Scanning Microscopy (CLSM) |
High resolution 3D point scanning microscopy |
2D and 3D cell cultures and systems |
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Light Sheet Microscopy (LSM) |
Fast 3D imaging with sub µm spatial resolution over large (mm-sized) sample volumes with reduced light exposure. |
3D cell cultures and multicellular systems, tissues and organisms. Long duration time lapse imaging |
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Two Photon Excited Fluorescence Microscopy (TPEFM) |
Deep 3D imaging inside a range of samples |
2D and 3D cell cultures and systems, tissues and organisms. |
Typical applications include:
These services are delivered using the following equipment:
We also have supporting facilities for cell culture and microbiology (Cat 2 laboratoires), sample preparation (mounting and fluorescent labelling) and optogenetics.
Don’t see what you are looking for? Our diverse skill set enables us to provide bespoke solutions. Please contact us to discuss your requirements.
Our team of experts develops and uses range of cutting-edge measurement tools and methods to create new treatments and diagnostics, as well as make current ones more effective.
We develop cutting edge measurement tools and methods to unlock new applications, from drug discovery to synthetic biology. Our knowledge of biophysical measurements helps us understand the relationship between biological systems and processes.
Our research and measurement solutions support innovation and product development. We work with companies to deliver business advantage and commercial success.
Contact our Customer Services team on +44 20 8943 7070
