Applying our knowledge of MSI imaging techniques to support healthcare, life sciences and other industries
We are constantly improving our resolution and broadening the applications for mass spectrometry imaging (MSI). Our experienced team, combined with our world leading range of imaging techniques, offers novel and unique capabilities to help solve customer problems.
Examples of this include:
Skin and hair health: NPL can provide label-free visualisation of formulations and their penetration into dermal tissue and hair structure. In the case of skin tissue samples, identification of the penetration pathway, such as follicular or transcellular, is possible. We also offer chemical characterisation of formulations, including co-localisation of the ingredients, demixing and crystallisation.
Medical device development: We support medical device development by determining root causes of device failure, device/host interactions and origins of a surface contaminations. This improves manufacturing processes and reliability, and meets the quality control and regulatory requirements.
Tissue imaging: Localised molecular information provides the opportunity to directly investigate the link between tissue structure and function, and MSI has been established as a powerful technique for achieving this. We offer services for industry and academia in a range of techniques for mass spectrometry imaging of small and large molecules, at resolutions suitable for probing sub-cellular, cellular and whole tissue features.
Computational analysis tools for large multi-modal data: Our diverse range of surface and nano-analysis techniques often produce large, heterogeneous and complex multi-modal data. The computational capabilities we have developed allow the visualisation and analysis of these data, enhancing the understanding of particular problems or measurements. A wide range of machine learning, statistical, data-driven and exploratory data analysis methods enable us to extract all key information from these multiple data modalities.
Our computational expertise are readily transferable to general problems surrounding large scale data and analysis. Through measurement and consultancy services, we can provide the analysis and visualisation of data, or provide software, training and support for companies to mine their own data.
Find out more about our commercial services including surface, nano and biophyiscal characterision.