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Jascindra Ravi

Jascindra Ravi

Higher Research Scientist

Jascindra Ravi obtained an MSc in Bioanalytical Chemistry (instrumental methods in biological and environmental (pharmaceutical) chemistry) at the University of Warwick, where she stayed on to complete a PhD in Biophysical Chemistry. Her research involved structural characterisation of macromolecular interactions in the solution phase using polarized spectroscopic techniques, such as circular and linear dichroism. Within the research programme, new applications for flow linear dichroism including protein-membrane interactions and single-walled carbon nanotube-DNA interactions were explored. Finally, the potential of the new technique, infrared flow linear dichroism, was investigated with DNA.

Jascindra joined NPL to work on protein structure analysis, where she has spent her time validating circular dichroism (CD) for protein structure analysis and was involved in the development of a CD standard. This was followed by a period of developing FTIR as an early detection tool for methionine oxidation in biopharmaceuticals.

Currently, she is working on the development and application of measurement methods to advance the understanding of protein structure, assembly and function relationships at biomolecular interfaces. This involves the study of interactions between peptides such as antimicrobial peptides (AMP), cell penetrating peptides (CPP), HIV peptides and amyloid β peptides with artificial membranes using biophysical techniques.

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