TechniquesNational Centre of Excellence in Mass Spectrometry Imaging focuses on the fundamentals and metrology of key techniques, to boost applications and impact.
- DESI – Desorption Electrospray Ionisation Mass Spectrometry uses mass spectrometry to analyse ions desorbed from a surface by an electrospray, under ambient conditions.
- SIMS - Static Secondary Ion Mass Spectrometry uses mass spectrometry to analyse ions desorbed from a surface by an energetic primary ion beams, under vacuum conditions.
- In MALDI MS a matrix compound, usually a small organic acid, is applied to the sample surface, where co-crystallisation of the sample with the matrix takes place.