National Physical Laboratory

NiCE-MSI The National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI) focuses on the development, understanding and application of mass spectrometry imaging techniques; providing powerful eyes on the molecular and atomic world.

Mass spectrometry imaging (MSI) techniques provide powerful eyes on the molecular and atomic world: From the localisation of drugs and metabolites in cells and tissues to 3D imaging of advanced manufactured devices.

The National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI) aims to advance the development, understanding and application of the principal mass spectrometry imaging techniques: Secondary ion mass spectrometry (SIMS), matrix assisted laser desorption/ionisation mass spectrometry (MALDI-MS), and the family of atmospheric mass spectrometry techniques (DESI, LESA, PADI).

The objectives of NiCE-MSI are:

  • Understanding the fundamental principles and phenomena behind MSI techniques
  • Developing metrology for reliable measurement and standardisation in MSI
  • Innovation of novel instrumentation and validating emerging MSI applications
  • Data analytics for machine learning, visualisation and interpretation of MSI data
  • Supporting industrial, academic and government partners through collaborative R&D and measurement services
  • Training a new generation of scientists in MSI through collaborative PhD studentships and secondments

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