National Physical Laboratory

NiCE-MSI The National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI) focuses on the fundamentals and metrology of key techniques, to boost applications and impact.

Mass spectrometry imaging techniques provide powerful eyes on the molecular and atomic world. The principal techniques are secondary ion mass spectrometry (SIMS), ambient mass spectrometry (AMS) and matrix assisted laser desorption/ionisation mass spectrometry (MALDI MS). Recent advances allow molecules to be imaged in 3D, in real-time and ambient conditions and the distribution of large biomolecules to be studied.

The aims of NiCE-MSI are:

  • Fundamentals of techniques
  • Metrology for reliability and standardisation
  • To support the update of the techniques