National Physical Laboratory

Opportunity for contributing to nanoparticle standardisation

The National Physical Laboratory (NPL) is now recruiting participants to a VAMAS inter-laboratory comparison on number concentration of colloidal nanoparticles.

Opportunity for contributing to nanoparticle standardisation

Nanoparticles are increasingly used in innovative products manufactured by advanced industries and provide enhanced, unique properties of great commercial and societal value. The measurement of number concentration of particles in colloidal suspension is of major commercial interest as it enables the optimisation of materials specification and design, and is essential for risk assessment and quality control. It also supports compliance with regulation and underpins any claim to reliability, performance and lifetime in the formulation of products containing particles.

In recent years there have been substantial advances in the ability to directly measure particle concentration in colloidal suspension. However, no formal evaluation and validation of available techniques have taken place and nanoparticle reference materials that are certified for number concentration do not yet exist. NPL is launching an interlaboratory comparison (ILC) under the umbrella of VAMAS (Versailles Project on Advanced Materials and Standards) as the basis for standardisation activity in the measurement of number concentration of colloidal nanoparticles.

The ILC will request participants to measure the number concentration of 30 nm colloidal gold nanoparticles with at least one of four techniques:

  • UV-Vis spectrometry;
  • single-particle inductively coupled plasma mass spectroscopy (spICP-MS);
  • particle tracking analysis (PTA); and
  • differential centrifugal sedimentation (DCS)

The samples will be provided by NPL along with a protocol, while the contribution of the laboratories to the study is in kind. This is a great opportunity for the laboratory to take part into the development of the metrology in support of nanoparticle-based technologies. It is expected that outcomes from the study will be disseminated through a peer-reviewed scientific publication, good practice guides and will contribute to future standards (ISO, CEN, etc.) in the area.

This is also an opportunity to benchmark the performance of your laboratory and provide data in support of measurement service you may be offering. In any direct publication from the study, the lab identities will be coded. However, you have the choice to disclose your identity in any further paper you may want to produce independently.

NPL intends to distribute the materials for the study by the end of November 2017 and collect the results in February 2018. If you are interested in participating to the study (VAMAS TWA34, Project 10) with one of more of the listed techniques, please contact Caterina Minelli at NPL by 15 October 2017.

Keep in touch with the latest news and events at NPL
by signing up for an email newsletter

Last Updated: 12 Sep 2017
Created: 15 Aug 2017


Please note that the information will not be divulged to third parties, or used without your permission