National Physical Laboratory

Super-resolution microscopy for cellular imaging

Further Information

Published: 10 November 2011

Authors: M Erdélyi, A Knight, E Rees, D Metcalf, GS Kaminski Schierle, CF Kaminski

Related: Analytical Science, Biotechnology

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Instruments based on direct stochastic optical reconstruction microscopy (dSTORM) are used to image the absorption of proteins by cells.

The resolution of traditional microscopes is limited because of optical diffraction. Super-resolution imaging methods, like dSTORM, have been proposed to break this resolution barrier down and provide imaging at the molecular scale.

The work was in collaboration with scientists from the Department of Chemical Engineering and Biotechnology at the University of Cambridge.

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Last Updated: 9 Apr 2014
Created: 15 Nov 2011

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