Current Interests

Mike Shaw is currently working on the application of adaptive optics (AO) and wavefront sensing techniques to biomedical imaging, particularly fluorescence microscopy, where AO offers the potential of improving image resolution and depth penetration in complex specimens. He is also developing a high speed structured illumination super-resolution fluorescence microscope for live cell imaging beyond the diffraction limit. More generally Mike’s interests are in the practical and theoretical aspects of optical imaging, image processing and analysis and the characterisation of optoelectronic devices.

Biography

Mike joined NPL after completing an MSci in Physics at Imperial College London and began his career developing techniques for absolute measurement of the scattering and fluorescence properties of materials. He has also developed a spectroscopic system for measuring the spectral radiant intensity of light sources. Since 2007, his primary research interests have been the characterisation and application of adaptive optic and digital holographic devices to biomedical imaging and in quantitative biological imaging in general.

Selected Publications

• Three-Dimensional Cell Morphometry for the Quantification of Cell-Substrate Interactions
  M. Shaw, N. Faruqui, E. Gurdak, and P. Tomlins
  Tissue Engineering Part C-Methods, 19 (1), 48-56 (2013)
• Polarization effects on contrast in structured illumination microscopy
  K. O'Holleran and M. Shaw
  Optics Letters, 37, 4603-4605 (2012)
• Characterization of deformable mirrors for spherical aberration correction in optical sectioning microscopy
  M. Shaw, S. Hall, S. Knox, R. Stevens, C. Paterson
  Opt. Express, 18 (7), pages 6900-6913 (2010)
• Array-based goniospectroradiometer for measurement of spectral radiant intensity and spectral total flux of light sources
  M. Shaw, T. Goodman
  Applied Optics, 47 (14), pages 2637-2647 (2008)

Contact details

E-mail: mike.shaw@npl.co.uk
Tel: 020 8943 6646