National Physical Laboratory

New test detects drug use from a single fingerprint

Researchers from the National Physical Laboratory (NPL), the University of Surrey, the Netherlands Forensic Institute, King's College London and Sheffield Hallam University have demonstrated a new, non-invasive test that can detect cocaine use through a simple fingerprint. For the first time, this new fingerprint method can determine whether cocaine has been ingested, rather than just touched.

Image courtesy of iStockphoto
Courtesy of iStockphoto

The research, published in the journal Analyst, used different types of an analytical chemistry technique known as mass spectrometry to analyse the fingerprints of patients attending drug treatment services. They tested these prints against more commonly used saliva samples to determine whether the two tests correlated. While previous fingerprint tests have employed similar methods, they have only been able to show whether a person had touched cocaine, and not whether they have actually taken the drug.

"When someone has taken cocaine, they excrete traces of benzoylecgonine and methylecgonine as they metabolise the drug, and these chemical indicators are present in fingerprint residue," said lead author Dr Melanie Bailey from the University of Surrey.

"For our part of the investigations, we sprayed a beam of solvent onto the fingerprint slide (a technique known as Desorption Electrospray Ionisation, or DESI) to determine if these substances were present. DESI has been used for a number of forensic applications, but no other studies have shown it to demonstrate drug use."

DESI analysis was carried out at the National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI) at NPL.

Researchers believe that the applications for this test could be far-reaching. Drug testing is used routinely by probation services, prisons, courts and other law enforcement agencies. However, traditional testing methods have limitations. For example, blood testing requires trained staff and there are privacy concerns about urine testing. Where bodily fluids are tested, there can be biological hazards and often a requirement for particular storage and disposal methods. Often these tests also require analysis off-site.

"The beauty of this method is that, not only is it non-invasive and more hygienic than testing blood or saliva, it can't be faked," added Dr Bailey. "By the very nature of the test, the identity of the subject is captured within the fingerprint ridge detail itself."

It is anticipated that this technology could see the introduction of portable drug tests for law enforcement agencies to use within the next decade.

"We are only bound by the size of the current technology. Companies are already working on miniaturised mass spectrometers, and in the future portable fingerprint drugs tests could be deployed. This will help to protect the public and indeed provide a much safer test for drug users," said Dr Bailey.

Find out more about NPL's work on Surface & Nanoanalysis

For further information, please contact Felicia Green

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Last Updated: 8 Jul 2015
Created: 15 May 2015

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