National Physical Laboratory

Biotechnology Publications

Biotechnology Group Publications since 2010

Primary Research

Polarization effects on contrast in structured illumination microscopy
O’Holleran K and Shaw MJ
Optics Letters, 201237, 4603-4605

Optical scattering artifacts observed in the development of multiplexed surface enhanced Raman spectroscopy nanotag immunoassays
Noble J, Attree S, Horgan A, Knight A, Kumarswami N, Porter R, Worsley G
Analytical Chemistry, 2012, 84(19), 8246-52

Three-Dimensional Cell Morphometry for the Quantification of Cell-Substrate Interactions
Shaw MJ, Faruqui N, Gurdak E, Tomlins P
Tissue Engineering, 2012

Rapid duplex immunoassay for wound biomarkers at the point-of-care
Worsley GJ, Attree SL, Noble JE, Horgan AM
Biosens. Bioelectron. 2012, 34, 215-220

Metallopolymer-peptide hybrid materials: synthesis and self-assembly of functional, polyferrocenylsilane-tetrapeptide conjugates
Tangbunsuk S, Whittell GR, Ryadnov MG, Vandermeulen GW, Woolfson DN, Manners I.
Chem. Eur J. 2012, 18, 2524-2535

Natively unfolded state for engineering nanoscale fibrillar arrays
Ryadnov M. G., Cherny D. I.
Macromol. Biosci., 2012, 12, 195-201

Membrane mediated regulation in free peptides of HIV-1 gp41: minimal modulation of the hemifusion phase
Cerasoli E., Ravi J., Gregor C. R., Hussain R., Siligardi G., Martyna G. J., Crain J., Ryadnov M. G.
Phys. Chem. Chem. Phys., 2012, 14, 1277-1285

Arbitrary self-assembly of peptide extracellular microscopic matrices
Bella A., Ray S., Shaw M., Ryadnov M. G.
Angew. Chem. Int. Ed., 2012, 51, 428-431

Random coil: a-helix equilibria as a reporter for the LewisX-LewisX interaction
Altamore TM, Fernández-García C, Gordon AH, Hübscher T, Promsawan N, Ryadnov MG, Doig AJ, Woolfson DN, Gallagher T
Angew. Chem. Int. Ed., 2011, 50, 11167-11171

Map-free line-scanning tomographic optical microscope
Sinkó J, Dudás L, Gajdátsy G, Erdélyi M, Szabó G
Opt. Lett., 2011, 36, 4011-4013

GeT peptides: a single-domain approach to gene delivery
Lamarre B, Ravi J, Ryadnov MG
Chem. Comm., 2011, 47, 9045-9047

In Situ Measurements of the Formation and Morphology of Intracellular β-Amyloid Fibrils by Super-Resolution Fluorescence Imaging
Kaminski Schierle GS, Sebastian van de Linde S, Erdelyi M, Esbjrner EK, Klein T, Rees E, Bertoncini CW, Dobson CM, Sauer M, Kaminski CF
J. Am. Chem. Soc., 2011, 133, 12902–12905

Antibody Recognition of the epitope (hCG{beta}66-80) depends on local structure retained in the free peptide
Gregor CR, Cerasoli E, Schouten J, Ravi J, Slootstra J, Horgan A, Martyna GJ, Ryadnov MG, Davis P, Crain J
J. Biol. Chem., 2011 286, 25016-25026

Bayesian analysis of an international ELISA comparability study
Klauenberg K, Ebert B, Voigt J, Walzel M, Noble JE, Knight AE, Elster C
Clin. Chem. Lab. Med., 2011, 49(9), 1459-68

Silver nanoparticles and magnetic beads with electrochemical measurement as a platform for immunosensing devices
Szymanski M, Porter R, Dep GV, Wang Y, Haggett BGD
Phys. Chem. Chem. Phys. 2011, 13, 5383-5387

FTIR markers of methionine oxidation for early detection of oxidized protein therapeutics
Ravi J, Hills AE, Cerasoli E, Rakowska PD, Ryadnov MG
Eu. Biophys. J. 2011, 40, 339-345

Autonomous folding in the membrane proximal HIV peptide gp41659−671: pH tuneability at micelle interfaces
Gregor CR, Cerasoli E, Tulip PR, Ryadnov MG, Martyna GJ, Crain J
Phys. Chem. Chem. Phys. 2011, 13(1), 127-135

Chemical and biological characterisation of a sensor surface for bioprocess monitoring
Moore JD, Perez-Pardo MA, Popplewell JF, Spencer SJ, Ray S, Swann MJ, Shard AG, Jones W, Hills A, Bracewell DG
Bios. Bioelectron. 2011, 26(6), 2940-2947

Investigation of bovine serum albumin denaturation using ultrasonic spectroscopy
Povey MJW, Moore, JD, Braybrook J, Simons H, Belchamber R, Raganathan M, Pinfield V
Food Hydrocoll., 2011, 25, 1233-1241

Development of a candidate secondary reference procedure (immunoassay based measurement procedure of higher metrological order) for cardiac troponin I: I. Antibody characterization and preliminary validation
Noble JE, Bunk DM, Christenson RH, et al.
Clin. Chem. Lab. Med., 2010, 48(11), 1603-1610

MiS-MALDI: microgel-selected detection of protein biomarkers by MALDI-ToF mass spectrometry
Cerasoli E, Rakowska PD, Horgan A, Ravi J, Bradley M, Vincent B, Ryadnov MG
Mol. Biosyst., 2010, 6(11), 2214-2217

Conformational Plasticity in an HIV-1 Antibody Epitope
Tulip PR, Gregor CR, Troitzsch RZ, Martyna GJ, Cerasoli E, Tranter G, Crain J
J. Phys. Chem. B, 2010, 114(23), 7942-7950

International comparability in spectroscopic measurements of protein structure by circular dichroism: CCQM-P59.1
Ravi J, Rakowska P, Garfagnini T, Baron B, Charlet P, Jones C, Milev S, DeSa Lorenz J, Plusquellic D, Wein F*, Liqing Wu, Meuse CW, Knight AE
Metrologia, 2010, 47(6), 631-641

Characterization of deformable mirrors for spherical aberration correction in optical sectioning microscopy
Shaw M, Hall S, Knox S, Stevens R, Paterson C
Opt. Express, 2010, 18(7), 6900-6913

Standardisation of cardiac troponin I measurement: past and present
Tate JR, Bunk DM, Christenson RH, Katrukha A, Noble JE, Porter RA, Schimmel H, Wang L, Panteghini M
IFCC Working Group on Standardization of Troponin I, Pathology. 2010, 42, 402-408

Bioconjugation and characterisation of gold colloid-labelled proteins
Thobhani S, Attree S, Boyd R, Kumarswami N, Noble J, Szymanski M, Porter RA
J. Immunol. Methods, 2010, 356(1-2), 60-69

Electrochemical dissolution of silver nanoparticles and its application in metalloimmunoassay
Szymanski M, Turner APF, Porter R
Electroanalysis, 2010, 22(2), 191-198

Reviews, commentaries, chapters and notes


Prescriptive peptide design
Ryadnov MG
Amino Acids, Pept. Proteins.(Farkas, E., Ryadnov, M. G., eds.) RSC Publishing, 2012, 37, 190-237

Amino Acids, Peptides and Proteins
Farkas E, Ryadnov MG
Amino Acids, Pept. Proteins., RSC Publishing 2012, 37, 270 pp

Biomimetic self-assembling nanoparticles
Ryadnov MG
Adv. Drug Deliv. (ed. Mitra AK, Lee CH, Cheng K) 2012 (in press)

Collaborative research leads to new understanding of biomarkers
Ryadnov MG, Crain J
Drug Discov. World 2012, 13, 61-66

Viscosity of concentrated therapeutic protein composition
Jezek J, Rides M, Derham B, Moore J, Cerasoli E, Simler R, Perez-Ramirez B
Adv. Drug Deliv. Rev., 2011

FT-IR markers of methionine oxidation
Ravi J, Ryadnov M
Bruker Optics Application Note AN#93, 2011, BOPT-110613-1

Single Enzyme Studies: A Historical Perspective
Knight A
Single Molecule Enzymology
Methods Mol. Biol.
, 2011, 778, 1-9

Nano-enabled biomarker discovery and detection
Rakowska PD, Ryadnov MG
Biomark. Med., 2011, 5, 387-396

Cellular uptake and intracellular fate of engineered nanoparticles: A review on the application of imaging techniques
Tantra R, Knight A
Nanotoxicology, 2011, 778, 1-9

The rational development of molecularly imprinted polymer-based sensors for protein detection
Whitcombe MJ, Chianella I, Larcombe L, Piletsky SA, Noble J, Porter R, Horgan A
Chem. Soc. Rev., 2011, 40, 1547-1571

Self-assembling viral mimetics: one long journey with short steps
Lamarre B, Ryadnov MG
Macromol. Biosci., 2011, 11, 503-513

Translational biophysics: physical sciences for molecular medicine
Ryadnov, MG, Cerasoli E, Martyna GJ, Crain J
Future Med. Chem. 2010, 2, 1633-1639

Polymer- and colloid-mediated bioassays, sensors and diagnostics
Horgan AM, Moore JD, Noble JE, Worsley GJ
Trends in Biotechnol., 2010, 28, 485-494

Changing concepts in the characterisation of microbes and the influence of mass spectrometry
H N Shah, et al.
Mass Spectrometry for Microbial Proteomics (ed. H. Shah and S. Gharbia), 2010, Wiley-VCH: Berlin, Chapter 1

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