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Biotechnology

Biotechnology Services

The Biotechnology Group offers a range of measurement services to help those developing biopharmaceuticals and biodiagnostic devices.

If you cannot find what you are looking for, please contact us.

Characterisation of nanoparticles and colloids

  • http://www.pdb.org/pdb/explore/explore.do?structureId=1K4RSize
  • Polydispersity
  • Density
  • Surface charge
  • Surface coverage
  • Stability
  • Molecular weight

Characterisation of proteins, antibodies and nucleic acids

  • Antibody pairing, epitope specificity analysis and lead verification
  • Association / dissociation constants
  • http://dx.doi.org/10.2210/pdb3aeb/pdb
    Kinetics and thermodynamics
  • Molecular weight
  • Aggregation state and stability
  • Structure and conformation
  • Chemical composition
  • Formulation

Assay development

  • Immunoassays (lateral flow and ELISA)
  • Point-of-care reader design and development
  • Solution, surface and cellular
  • Single Molecule FluorescenceRaman, fluorescence, electrochemical and visual
  • Molecular binders (aptamers, molecular imprinted polymers)
  • Antibody-nanoparticle conjugation
  • Surface chemistry
  • Single molecule
  • Assay validation

Small molecule characterisation

  • Purity
  • Molecular weight
  • Chemical composition
  • BiotechnologyLead verification

Protein chemistry and biophysics

  • Protein and polypeptide structure and folding
  • Protein aggregation and stability
  • Peptide synthesis and characterisation (mg-g scale)
  • Protein/peptide identification and mass-determination (PMF/PSD)
  • Bioconjugation and labelling
  • Surface immobilisation
  • Protein kinetics

Biotechnology

Bioaerosol monitoring (in collaboration with the Environmental Group)

  • Aspergillus Fumigatus
  • Other organisms possible




For more information on Biotechnology services, please contact Dr James Noble